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Clinical

Dermagio

Dermagio

Photoacoustic dermatological imaging device

The Dermagio imaging device supports dermatological diagnosis, treatment monitoring, and research. Utilizing advanced photoacoustic technology, Dermagio visualizes microvessels beneath the skin and segments them into anatomical layers—offering structural and functional insights that go beyond traditional imaging methods.

Dermagio consists of three core components: a laser subsystem that delivers imaging light, a handheld photoacoustic probe for direct skin contact, and a control unit for system operation and data processing.

In evaluating skin conditions, Dermagio’s dedicated software enables intuitive visualization and quantitative analysis. Volumetric image data provides depth-resolved information, and skin layers can be segmented based on anatomical structures for independent evaluation. This segmentation also enables advanced applications, such as assessing vasoconstrictive responses or monitoring therapeutic efficacy.

Applications

Anatomical layer imaging

Immune and inflammatory skin diseases

Skin cancer (both melanoma and non melanoma)

Vascular conditions and structural imaging

Diagnosis and treatment monitoring of melasma in the epidermis and dermis

Clinical assessment of dermatological agents.

Microneedle research

Skin ageing and skin quality

Tumor progression and regression monitoring

Advantages

Layer by layer visualization of subdermal microvessels and pigments

Endogenous hemoglobin and melanin allow for daily monitoring

Optics, acoustics, and electronics are configured in one movable unit

A single button on the probe initiates two imaging modes (pre- and standard diagnosis)

Image and quantitative results available immediately after examination

Dermagio System Configuration

Dermagio System Operation

Real-time software interface during imaging

Operating the handheld probe

Dermagio Specifications

Spatial resolution Lateral resolution (Y-axis): 7.3 μm
Axial resolution: 57 μm
Elevational resolution (X-axis): 5.0 μm
Geometric accuracy X-axis: 97.5%
Y-axis: 95.5%
Imaging speed1 Cross section (B-scan): 125 Hz
Volumetric imaging time: 1.2 sec for 4 x 4 mm²
Sensitivity 84mV/mM in Evans Blue dye
Field of view ~ 4 x 4 mm²
Depth detection Max imaging depth < 1.8 mm
Dynamic range 15.18 - 47.27 dB

1 The B-scan speed depends on the step size and pulse repetition rate of the laser.

Dermagio Demo Movie

Dermagio Gallery

Human vascular imaging: palm

 

MAP

Cross sectional view

Surface(Depth) view

Human vascular imaging: tongue

 

MAP

Cross sectional view

Surface(Depth) view

Human vascular imaging: lower lip

 

MAP

Cross sectional view

Surface(Depth) view

Human vascular imaging:  ear

 

MAP

Cross sectional view

Surface(Depth) view

Pigmented skin lesions imaging: facial melasma

 

MAP

Cross sectional view

Surface(Depth) view

Pigmented skin lesions imaging: nevus on the upper arm

 

MAP

Cross sectional view

Surface(Depth) view